Wednesday, July 29, 2020

Basal Ganglia


Basal Ganglia:  Questions
1. Caudate and putamen collectively forms the striatum.
Ans: True [Ganong 26th ed.pg-239

2. Putamen and GP forms lenticular nucleus.
Ans: True. [Ganong 26th ed .pg-239.

3. Parkinson’s disease is also called as paralysis agitans.
Ans: True [Guyton 11th ed.pg-711]

4. Putamen circuit has its inputs mainly from parts of the brain               to primary motor cortex and output fibers enter mainly into                  .

Ans: adjacent, primary motor cortex.


5.  -------- extends into all lobes of cerebrum and forming a letter like ‘C’.

Ans: caudate. [Guyton 11th ed.pg-709


6. ----------is responsible for the psychic drive for motor activity.
Ans: Nucleus Accumbens.

7. Striatal neurons --------the thalamus via the direct pathway.

Ans: excite. [G.K pal.pg- 832]

8. Sydenham’s chorea occurs following --------------infection.
Ans: streptococcal infection

9. Anterior cingulated circuits are important for -----------------
Ans: procedural learning.

10. Abnormal gene responsible for Huntington disease is located in ----------
Ans: short arm of Ch4[Ganong pg-241

1. What is Basal ganglia stroke?
Decreased blood supply to BG.leads to stiff muscles, tremor, memory loss, depression, anxiety etc.Recovery occurs in a month or so, but not every patient recovers on their own. It needs rehabilitation.

2. What is lacunar stroke?
Lacunar stroke –lacunar infarct –occlusion of deep penetrating arteries from circle of Willis.

Saturday, July 25, 2020

Basal ganglia-MCQs


1. Tremor of Parkinson’s disease is
a. an involuntary tremor
b. an intention tremor
c. pill rolling type
d. a+c is correct
Ans: d. Ganong 26thed, pg-241, Guyton 11th ed, pg -711

2. Wilson’s disease is also called as
a. Huntington disease
b.Hepatolenticular degeneration
c.OCD
d.ADHD
Ans: b.Ganong 26th Pg-241

3. Parkinsonism is seen as a complication of treatment with

a.L.Dopa
b.Phenothiazine
c.Bromocriptine
d.Carbidopa
Ans: b.Ganong26th Pg-243

4. Which of the following statements is false?
a.Nigrostriatal pathway is the most severely affected in Parkinson’s disease [PD].
b.MAO inhibitors are useful in the treatment of PD.
c.Lewy bodies are inclusion bodies occur in PD
d.clasp-knife rigidity is a characteristic feature of PD.
Ans: d.Guyton -pg-115, Ganong, pg-243.

5. The characteristic gait in PD is called
a.circumduction gait
b.waddling gait
c.festinant gait/shuffling
d.drunken gait
Ans: c. Indu khurana, pg-962

6. Which of the following statements is correct?
a.SN PC releases dopamine to excite GpE
b.SN PR releases dopamine to inhibit striatum.
c.SN PC releases dopamine to inhibit striatum.
Ans: c. Ganong, pg-239

7. Which of the following statements is correct?
A.Subthalamic nucleus releases Glutamate to inhibit GpI
b.subthalamic nucleus releases Glutamate to excite GpI.
c.GpE releases Glutamate to excite striatum.
Ans: b. Ganong, pg-239

8. The caudate circuit is essential for
a. Motor coordination of fine movement
b.cognitive control of sequence motor pattern
c.motor coordination of crude movement
d.none of the above
Ans: b.Guyton, pg-709


9. The dopamine pathway in BG is predominantly from
a. Caudate to putamen
b.cortex to caudate
C. Gp to Sub Th
d. SN to caudate
Ans: d.Guyton, 709, Ganong, pg-239

10. Mutations of proteins found in Lewy bodies are
A.Frataxin and ataxin
b.synuclein and parkin
c.DM protein kinase
d.FMR-1
Ans: b.Ganong, pg-242





Friday, July 3, 2020

I M.B.B.S Online symposia schedule


DEPARTMENT OF PHYSIOLOGY,THANJAVUR MEDICAL COLLEGE
UNDERGRADUATE SYMPOSIA I-MBBS (2019-2020 BATCH)

1)       Roll No.8 - 09.07.2020 - 11-11.30AM - ANNAPURNA SAVALAM -[NEUROMUSCULAR JUNCTION]
2)       Roll No.106 - 09.07.2020 - 11.30AM-12N - SAKTHI THANGAVEL.A-[CROSS BRIDGE CYCLE IN SMOOTH MUSCLE]
3)        Roll No.137 - 10.07.2020 - 11-11.30AM - THIRUMAL.R - [OSMOLALITY OF ECF AND ICF]
4)       Roll No.140 - 10.07.2020 -  11.30AM-12N - VENKATESH KUMAR.R - [PRESSURE CHANGES AND AIRFLOW DURING BREATHING]
5)       Roll No.55 -- KAILASANATHAN.V -[ COMPENSATORY MECHANISM FOLLOWING BLOOD LOSS]
6)       Roll No.105  - RITHISH.R - [AUTOREGULATION OF BLOOD FLOW]
7)       Roll No.20 -- DEEBIKA.P - [REGULATION OF BODY TEMPERATURE]
8)       Roll No.6 -- KIRTHANA.R - [NEURAL CONTROL OF DIGESTIVE FUNCTION]
9)       Roll No.101  --RAMANAN.T.T -[ ABO BLOOD GROUP]
10)   Roll No.57 -- KAUSHIK.P.S -[CALCIUM HOMEOSTASIS]
11)   Roll No.34 -- GOKULAKRISHNAN.S -[ SEX DIFFERENTIATION AND DETERMINATION]
12)   Roll No.121 -- SNEHA.K - [PHYSIOLOGY OF AGEING]
13)   Roll No.6 -- AKASH SOORAJ SINGH.J -[ HORMONAL RESPONSE TO STRESS]
14)   Roll No.131 -- SURENDHAR.G -[ ELECTRICAL ACTIVITY IN GIT]
15)   Roll No.63 -- KRITHIK SANJAY.L - [CHEMICAL REGULATION OF RESPIRATION]
16)   Roll No.16 -- ASHWIN.K -[ PACEMAKER OF HEART]
17)   Roll No.124 -- SRINIVASAN JEEVAVARDHINI -[ FUNCTIONS OF THE VESTIBULAR APPARATUS]
18)   Roll No.50 -- JEES BENNY - [ BARORECEPTOR REFLEX]
19)   Roll No.91 -- PRADEESH.M -[ SECOND MESSENGERS]
20)   Roll No.12 – SRUTHI -[ CARDIAC CYCLE]
21)   Roll No.56 -- KATHIRVELAN.K -[ RESTING MEMBRANE POTENTIAL]