Basal ganglia-MCQs

1. Tremor of Parkinson’s disease is

a. an involuntary tremor

b. an intention tremor

c. pill rolling type

d. a+c is correct

Ans: d. Ganong 26^thed, pg-241, Guyton 11^th ed, pg -711

2. Wilson’s disease is also called as

a. Huntington disease

b.Hepatolenticular degeneration

c.OCD

d.ADHD

Ans: b.Ganong 26^th Pg-241

3. Parkinsonism is seen as a complication of treatment with

a.L.Dopa

b.Phenothiazine

c.Bromocriptine

d.Carbidopa

Ans: b.Ganong26th Pg-243

4. Which of the following statements is false?

a.Nigrostriatal pathway is the most severely affected in Parkinson’s disease [PD].

b.MAO inhibitors are useful in the treatment of PD.

c.Lewy bodies are inclusion bodies occur in PD

d.clasp-knife rigidity is a characteristic feature of PD.

Ans: d.Guyton -pg-115, Ganong, pg-243.

5. The characteristic gait in PD is called

a.circumduction gait

b.waddling gait

c.festinant gait/shuffling

d.drunken gait

Ans: c. Indu khurana, pg-962

6. Which of the following statements is correct?

a.SN PC releases dopamine to excite GpE

b.SN PR releases dopamine to inhibit striatum.

c.SN PC releases dopamine to inhibit striatum.

Ans: c. Ganong, pg-239

7. Which of the following statements is correct?

A.Subthalamic nucleus releases Glutamate to inhibit GpI

b.subthalamic nucleus releases Glutamate to excite GpI.

c.GpE releases Glutamate to excite striatum.

Ans: b. Ganong, pg-239

8. The caudate circuit is essential for

a. Motor coordination of fine movement

b.cognitive control of sequence motor pattern

c.motor coordination of crude movement

d.none of the above

Ans: b.Guyton, pg-709

9. The dopamine pathway in BG is predominantly from

a. Caudate to putamen

b.cortex to caudate

C. Gp to Sub Th

d. SN to caudate

Ans: d.Guyton, 709, Ganong, pg-239

10. Mutations of proteins found in Lewy bodies are

A.Frataxin and ataxin

b.synuclein and parkin

c.DM protein kinase

d.FMR-1

Ans: b.Ganong, pg-242